Scholarlink

Purpose <p>To evaluate the impact of young donor age on perioperative and early postoperative outcomes in DMEK.</p> Methods <p>In this retrospective study, 40 patients underwent DMEK using donor tissue sourced from either individuals younger than 40&#xa0;years (Group 1, <i>n</i> = 20; age range: 19–39&#xa0;years) or individuals older than 40&#xa0;years (Group 2, <i>n</i> = 20; age range: 41–76&#xa0;years). Data collected included recipient age, gender, diagnosis, preoperative visual acuity, donor age, ECD, graft diameter, intraoperative graft preparation time, unscrolling time, surgical complications, and graft survival at 3&#xa0;months. These parameters were compared between the two groups.</p> Results <p>There were no statistically significant differences between the groups in recipient demographics, preoperative visual acuity, donor characteristics (age, ECD, diameter), graft preparation time, unscrolling time, or corneal clarity at 3&#xa0;months (<i>p</i> &gt; 0.05). Minor tears occurred in two cases in Group 1 and one case in Group 2, but these grafts were still usable. Only one patient in Group 2 required a replacement graft due to a large tear. Resistant peripheral graft folds were observed in nine cases in Group 1 and one in Group 2, but none required postoperative rebubbling or led to surgical failure.</p> Conclusion <p>The use of young donor tissue in DMEK does not appear to negatively impact surgical outcomes. Further studies with longer follow-up are needed to assess long-term graft survival and validate the broader use of young donors in DMEK.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Use of very young donor grafts in descemet membrane endothelial keratoplasty: perioperative and early postoperative observations

  • 期刊论文

  • 发表日期：

    2025年12月15日

查看全文
  • Necip Kara,
  • Nilüfer Yeşilırmak,
  • Döndü Melek Ulusoy,
  • Serhat Ayla,
  • Bekir Eren Aksoy

摘要

Purpose

To evaluate the impact of young donor age on perioperative and early postoperative outcomes in DMEK.

Methods

In this retrospective study, 40 patients underwent DMEK using donor tissue sourced from either individuals younger than 40 years (Group 1, n = 20; age range: 19–39 years) or individuals older than 40 years (Group 2, n = 20; age range: 41–76 years). Data collected included recipient age, gender, diagnosis, preoperative visual acuity, donor age, ECD, graft diameter, intraoperative graft preparation time, unscrolling time, surgical complications, and graft survival at 3 months. These parameters were compared between the two groups.

Results

There were no statistically significant differences between the groups in recipient demographics, preoperative visual acuity, donor characteristics (age, ECD, diameter), graft preparation time, unscrolling time, or corneal clarity at 3 months (p > 0.05). Minor tears occurred in two cases in Group 1 and one case in Group 2, but these grafts were still usable. Only one patient in Group 2 required a replacement graft due to a large tear. Resistant peripheral graft folds were observed in nine cases in Group 1 and one in Group 2, but none required postoperative rebubbling or led to surgical failure.

Conclusion

The use of young donor tissue in DMEK does not appear to negatively impact surgical outcomes. Further studies with longer follow-up are needed to assess long-term graft survival and validate the broader use of young donors in DMEK.