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Purpose <p>To evaluate the precision, safety, and efficacy of congenital cataract surgery performed using the 27-gauge vitrectomy system in infants.</p> Methods <p>This retrospective study analyzed 44 eyes from 22 pediatric patients (aged 3–5&#xa0;months) with bilateral congenital cataracts. The following parameters were assessed: intraocular pressure, corneal diameters, axial length, and the occurrence of intraoperative and postoperative complications. Visual function was evaluated based on visual behavior in response to various stimuli. All patients were followed for a minimum of 6&#xa0;months.</p> Results <p>A significant reduction in intraocular pressure was observed (from 15.8 ± 5.7&#xa0;mmHg preoperatively to 12.2 ± 1.1&#xa0;mmHg postoperatively, <i>p</i> = 4.64 × 10⁻<sup>7</sup>). The average duration of the surgical procedure was 30 ± 5&#xa0;min. Postoperative complications were minimal and transient, including conjunctival hyperemia in 30% of eyes (resolved within one week) and mild anterior chamber reaction in 12% of eyes. No significant complications, such as retinal detachment or glaucoma, were observed during follow-up.</p> Conclusion <p>The use of the 27-gauge vitrectomy system for congenital cataract surgery in infants provides high surgical precision, low complication rates, and effective postoperative outcomes. Further prospective studies with longer follow-up are needed to confirm the long-term safety and efficacy of this approach.</p>

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Precision and efficacy in congenital cataract surgery: a retrospective study of the 27-gauge vitrectomy system

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年12月22日

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  • Maura Mancini,
  • Alessandro Meduri,
  • Claudio Brancato,
  • Giovanni William Oliverio,
  • Laura De Luca,
  • Alessandra Mancini,
  • Paola Palino,
  • Pasquale Aragona,
  • Antonino Pioppo,
  • Gregorio Lo Giudice

摘要

Purpose

To evaluate the precision, safety, and efficacy of congenital cataract surgery performed using the 27-gauge vitrectomy system in infants.

Methods

This retrospective study analyzed 44 eyes from 22 pediatric patients (aged 3–5 months) with bilateral congenital cataracts. The following parameters were assessed: intraocular pressure, corneal diameters, axial length, and the occurrence of intraoperative and postoperative complications. Visual function was evaluated based on visual behavior in response to various stimuli. All patients were followed for a minimum of 6 months.

Results

A significant reduction in intraocular pressure was observed (from 15.8 ± 5.7 mmHg preoperatively to 12.2 ± 1.1 mmHg postoperatively, p = 4.64 × 10⁻7). The average duration of the surgical procedure was 30 ± 5 min. Postoperative complications were minimal and transient, including conjunctival hyperemia in 30% of eyes (resolved within one week) and mild anterior chamber reaction in 12% of eyes. No significant complications, such as retinal detachment or glaucoma, were observed during follow-up.

Conclusion

The use of the 27-gauge vitrectomy system for congenital cataract surgery in infants provides high surgical precision, low complication rates, and effective postoperative outcomes. Further prospective studies with longer follow-up are needed to confirm the long-term safety and efficacy of this approach.