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Purpose <p>This study aims to characterize retinal and vitreous morphological changes in peripheral lattice degeneration using ultra-wide-field optical coherence tomography angiography (UWF-OCTA) guided by scanning laser ophthalmoscope (SLO) and to provide illustrative clinical applications.</p> Methods <p>A total of 15 eyes from 15 patients with peripheral retinal lattice degeneration were enrolled between January 2024 and March 2024. Peripheral lattice lesions were localized by SLO, followed by optical coherence tomography (OCT) and UWF-OCTA to evaluate retinal and vitreous changes.</p> Results <p>UWF-OCTA identified diverse retinal and vitreous changes in LD, including vitreous traction, retinal rupture, retinal thinning, vitreous detachment, and subretinal fluid collection. Clinical cases demonstrated that UWF-OCTA may detect lesion details missed by OCT, especially tiny retinal rupture holes.</p> Conclusion <p>UWF-OCTA enables high-resolution imaging of peripheral retina and comprehensive visualization of retinal and vitreous changes across lesion areas. SLO-guided UWF-OCTA shows potential as a supplementary imaging tool for visualizing subtle retinal lesions in peripheral lattice degeneration, laying the groundwork for future studies on its role in guiding clinical decisions.</p>

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Application of ultra-wide-field optical coherence tomography angiography in detecting peripheral lattice degeneration

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年11月3日

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  • Chunyang Cai,
  • Peiyu Liu,
  • Qingquan Wei,
  • Jiawei Huang,
  • Lan Yi,
  • Fang Wei,
  • Qinghua Qiu,
  • Chao Song

摘要

Purpose

This study aims to characterize retinal and vitreous morphological changes in peripheral lattice degeneration using ultra-wide-field optical coherence tomography angiography (UWF-OCTA) guided by scanning laser ophthalmoscope (SLO) and to provide illustrative clinical applications.

Methods

A total of 15 eyes from 15 patients with peripheral retinal lattice degeneration were enrolled between January 2024 and March 2024. Peripheral lattice lesions were localized by SLO, followed by optical coherence tomography (OCT) and UWF-OCTA to evaluate retinal and vitreous changes.

Results

UWF-OCTA identified diverse retinal and vitreous changes in LD, including vitreous traction, retinal rupture, retinal thinning, vitreous detachment, and subretinal fluid collection. Clinical cases demonstrated that UWF-OCTA may detect lesion details missed by OCT, especially tiny retinal rupture holes.

Conclusion

UWF-OCTA enables high-resolution imaging of peripheral retina and comprehensive visualization of retinal and vitreous changes across lesion areas. SLO-guided UWF-OCTA shows potential as a supplementary imaging tool for visualizing subtle retinal lesions in peripheral lattice degeneration, laying the groundwork for future studies on its role in guiding clinical decisions.