<p>In various engineering applications, particularly pumping systems, two-phase flows that involve the simultaneous flow of two different states of matter are widely employed. For instance, in industrial settings, the utilization of an airlift pump is common for transferring air or other gases to lift liquid. Conversely, in diffusion-absorption refrigeration cycles, a bubble pump is employed to create a two-phase flow through fluid boiling. To comprehend the impact of design and operational parameters on the lift water bubble pump, a comprehensive theoretical study was undertaken. The engineering equation solver (EES) was utilized in this investigation to examine the influence of lift pipe diameter, heat flux, and mass flux on the performance of the bubble pump. The study’s findings revealed that a single set of optimal conditions and values cannot be universally applicable to the bubble pump. This is because each system possesses unique characteristics and operational parameters, leading to a distinct set of optimized parameters. The theoretical study on the lift water bubble pump underscores the significance of considering design and operational parameters while developing and operating pumping systems that employ two-phase flow. Moreover, it emphasizes the necessity for extensive research to establish optimal conditions and values tailored to the specific characteristics and operating parameters of each individual system.</p>