Scholarlink

<p>Primates share several disease agents with humans. Some of these are of high medical concern, impacting both primate conservation and human health. <i>Plasmodium</i> parasites, responsible for malaria disease, have been associated with primate infection, and some species can be transferred between humans and other primates. In Mexico, despite the increasing rates of environmental transformation and human encroachment into the wild, there is no information regarding the occurrence of malaria parasites in wild primates in the country. We employed noninvasive sampling and molecular diagnostic techniques to detect <i>Plasmodium</i> infections in 14 populations of <i>Alouatta pigra</i> and <i>Ateles geoffroyi</i> in southern Mexico. We screened primate fecal samples for <i>Plasmodium</i> DNA through qPCR, and sequenced cytochrome b (<i>cytb</i>) and cytochrome <i>c</i> oxidase subunit 3 (<i>cox3</i>) genes to identify parasites at the species level. We used Bayesian inference to assess the phylogenic position of the obtained <i>cytb</i> sequences. Prevalence of <i>Plasmodium</i> infection was 12% in <i>A. pigra</i> and 7% in <i>A. geoffroyi</i>. The highest percentage of <i>Plasmodium</i> infection in these primates coincides with areas of foci of human malaria in the country. We confirmed the presence of <i>P. falciparum</i> in three of 93 samples. Further studies are needed to assess the richness of <i>Plasmodium</i> species in Mexican primates and to understand disease dynamics at the interface between human and our fellow primates, along with its implications for both public health and primate conservation.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Plasmodium Infections in Wild Mexican Primates, with the Detection of P. falciparum

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年8月4日

查看全文
  • Brenda Solórzano-García,
  • Norberto Alonso Colín-García,
  • Andrea Chaves,
  • Miroslava Avila García

摘要

Primates share several disease agents with humans. Some of these are of high medical concern, impacting both primate conservation and human health. Plasmodium parasites, responsible for malaria disease, have been associated with primate infection, and some species can be transferred between humans and other primates. In Mexico, despite the increasing rates of environmental transformation and human encroachment into the wild, there is no information regarding the occurrence of malaria parasites in wild primates in the country. We employed noninvasive sampling and molecular diagnostic techniques to detect Plasmodium infections in 14 populations of Alouatta pigra and Ateles geoffroyi in southern Mexico. We screened primate fecal samples for Plasmodium DNA through qPCR, and sequenced cytochrome b (cytb) and cytochrome c oxidase subunit 3 (cox3) genes to identify parasites at the species level. We used Bayesian inference to assess the phylogenic position of the obtained cytb sequences. Prevalence of Plasmodium infection was 12% in A. pigra and 7% in A. geoffroyi. The highest percentage of Plasmodium infection in these primates coincides with areas of foci of human malaria in the country. We confirmed the presence of P. falciparum in three of 93 samples. Further studies are needed to assess the richness of Plasmodium species in Mexican primates and to understand disease dynamics at the interface between human and our fellow primates, along with its implications for both public health and primate conservation.