Current advances and future prospects of ER stress signaling and its chemical mitigation in plants

This opinion article offers a comprehensive analysis of recent developments in the exploration of endoplasmic reticulum (ER) stress signaling pathways and future opportunities for chemical mitigation strategies in plants. Encouraging results have been observed in the mitigation of ER stress in plants through the use of various chemical compounds commonly referred to as chemical chaperones; however, their mechanisms still require further exploration. The interconnectedness of stress responses is evident in the cross-talk between ER stress signaling and other stress signaling pathways. Additionally, the investigation of the role of ER stress signaling in plant defense and immunity has highlighted its significance in enhancing plant resistance. Looking ahead, future studies focusing on chemical mitigation of ER stress are positioned to provide valuable insights that can significantly expand our existing knowledge base. These advancements hold immense potential for enriching our understanding of ER stress signaling and facilitating the development of effective stress mitigation strategies in plants.