<p>Construction of pile foundations is generally costly, complex, and time-consuming. It is thus essential to properly understand the load-settlement behavior of piles and to develop a rational approach for pile design that considers subsoil and geological data of the area and the pile construction method. Load Transfer Method (LTM) is one of the most popular and efficient methods considering these aspects. However, the accuracy of LTM depends heavily on the development of location-specific load-transfer functions derived from fully instrumented static pile load tests conducted under similar ground conditions. This study focuses on the soils in the Ganges–Brahmaputra-Meghna (GBM) delta region, emphasizing that load-transfer functions are inherently site-specific and that equations generated for one region may not be applicable elsewhere. To achieve this objective, fully instrumented static load tests were conducted on trial piles in the GBM delta. The data from these tests were analyzed to investigate the load-transfer and load-settlement behavior of single piles in the region. Empirical correlations for shaft friction and end-bearing resistance of piles are formulated as a function of SPT-N value using data obtained from these instrumented test piles. These functions are subsequently used in the load transfer method developed by Coyle and Reese. An Excel-based computational tool was developed using Visual Basic for Applications (VBA) to perform iterative calculations of the load-settlement response and axial load distribution profiles of piles using the LTM. The comparison of simulated results with field data from the instrumented test piles demonstrated that the semi-analytical load transfer method provided predictions that closely matched the static load test results. The findings underscore the importance of using location-specific load-transfer functions to ensure accurate pile design in the GBM delta soils.</p>