<p>Driven by the dual-carbon strategy, green innovation, as a kernel element of the new quality productivity, is reconfiguring the path of high-quality development of the manufacturing industry. In view of the rigid requirements of green environmental protection, it is difficult for the manufacturing industry to realize green transformation only by itself, and the synergy of multiple subjects has become the key. In contrast to the limitations of traditional research focusing only on the two-subject perspective, this paper takes the unique perspective of synergy of multiple heterogeneous subjects in the green innovation network, incorporates the government's environmental regulation, manufacturing enterprises' production mode, and consumer's green preference into the research framework of the synergy mechanism of the green innovation network, constructs the three-party evolution game model of the government, manufacturing industry, and consumers, and simulates the effect of changes in the parameters of the network of heterogeneous subjects on the evolution of the synergy by using Matlab. evolution of the heterogeneous subjects. The study finds that the collaborative evolution of green innovation network subjects shows significant strategy dependence, in which the government regulation forms the core anchor of the evolutionary stabilization strategy through the dual mechanism of incentives and constraints; the consumers' willingness to pay for low carbon is heterogeneous depending on the type and intensity of the government's environmental regulation tools and the interaction between the manufacturing behaviors of the enterprises. This study innovatively reveals the dynamic coupling law of the behavioral strategies of heterogeneous subjects, and purposefully proposes the synergistic strategy of green innovation network of multiple heterogeneous subjects. Its theoretical contributions include: (1) constructing a dynamic evolution analysis framework of “institutional design-market response-technological leap”; (2) identifying the critical conditions for government-manufacturing-consumer synergy in the green innovation network synergy mechanism. The research results provide a new analytical paradigm for solving the “island effect” of green innovation in the manufacturing industry, and have decision-making reference value for improving the green innovation network governance system.</p>