<p>In recent years, climate change has emerged as a major factor contributing to food insecurity, which intensifies economic difficulties in Asian and African nations. Consequently, this study seeks to explore the interplay between climate change, food security, and economic growth. Utilizing the panel vector error correction model, we present three primary findings. Firstly, a co-integration relationship exists among food security, as measured by the Global Food Security Index (GFSI), Gross Domestic Product (GDP), and the Climate Risk Index (CRI). Secondly, both in the long and short term, the CRI, which serves as an indicator of climate risk, influences the GFSI in the Asian region. Over the long term, both the CRI and GDP have a significant impact on the GFSI. An increase in GDP correlates with improved food security, whereas heightened climate change risks, as indicated by the CRI, worsen food insecurity. In the short term, it is evident that the previous year’s variables-GFSI, GDP, and CRI-significantly influence the GFSI in both Asian and African regions. Thirdly, economic growth, as measured by GDP, plays a more substantial role in enhancing food security than climate change does. To alleviate the effects of climate change on food security, we advocate for the implementation of strong policies aimed at reducing greenhouse gas emissions and bolstering human resource capacity, especially in vulnerable areas like Asia. International collaboration and alignment with the Sustainable Development Goals (SDGs) are vital for developing integrated strategies. Contributions. The findings of this research underscore that bolstering food security and enhancing climate change resilience can exert a positive influence on economic growth, shedding light on crucial policy considerations and actions to mitigate the effects of climate change on food security and economies.</p>