<p>We analyse the tenures in and exits from part-time employment from the gender perspective, considering separately the “old” (Western European) and “new” (Eastern European) EU countries. Overall, poor health, older age, low education, and preceding unemployment or inactivity experiences hinder the transitions from part-time to full-time employment and simultaneously increase the odds of exiting via unemployment or inactivity. Household and macroeconomic covariates are more illustrative than individual characteristics in revealing the deeply rooted differences in the exit patterns from part-time employment across the sexes and sub-regions. Further, we show that part-time work is a relatively resilient employment pattern, especially among Western European women. Despite gender- and regional-based variations, full-time employment is the main exit channel from part-time employment in all cases. Thus, part-time employment serves to a high degree as a stepping stone into full-time jobs, which is additionally supported by the prevalence of prolonged durations of full-time employment arrangements when a spell of part-time employment expires. Though the fraction of spells of part-time employment resulting in employment discontinuity represents just 25–30% (depending on the sub-region and sex), the exclusion from paid employment among former part-time workers requires policy attention: nearly a third of all unemployment episodes following the termination of a spell of part-time employment last 12&#xa0;months or longer while analogous figures for inactivity tenures are more diverse and range between 40 and 60%.</p>