<p>This study offers an updated analysis of the effects of ocean plastic accumulation on human health and biodiversity within the food chain, covering the period from 2018 to 2023. Through a comprehensive review of relevant literature, a framework has been developed to visually illustrate the progression of plastics through the food chain. This framework emphasizes the intricate connections among four key elements: humans, plastics, biodiversity, and the food chain. By examining the cycle of challenges encountered during the phases of production, consumption, and disposal, the research reveals how these stages are interrelated. This perspective not only delineates the complexities involved but also identifies potential solutions, particularly by incorporating circular economy principles. Consequently, the study highlights the importance of understanding the impact of plastics on the food chain while proposing strategies grounded in circular economy concepts to mitigate plastic pollution throughout the three stages.</p>