Scholarlink

Background <p>Abdominopelvic abscesses are significant complications in patients with Crohn’s disease (CD), often necessitating individualized management approaches. This study evaluates real-world treatment patterns and outcomes of CD-related abdominopelvic abscesses.</p> Methods <p>This retrospective cohort study included adult patients with CD developing disease-related abdominopelvic abscesses between January 2017 and October 2021. Initial management was at the discretion of treating physicians and categorized as surgery, interventional radiology (IR)-guided procedures, or medical therapy. Patients were followed for 2&#xa0;years. Primary outcomes included rates of salvage surgery and salvage IR-guided procedures, defined as additional unplanned treatment following the initial management approach. Secondary outcomes included any surgery within 2&#xa0;years, including planned or delayed surgical intervention.</p> Results <p>A total of 93 patients were included. Initial management included surgery in 25 (27%), IR-guided procedures in 35 (38%), and medical therapy alone in 33 patients (35%). Surgery was required in 60% within 2 years and 69% within 3 years. No variables were significantly associated with the need for surgery at 2 years on multivariable analysis. Salvage treatment was most frequent in the medical therapy group (39%) followed by IR (26%). Initial surgery was associated with presence of multiple abscesses (≥ 3 in 28% vs. 9% IR 3% medical; overall p = 0.047), while IR-drainage was associated with larger abscesses (median 5.0&#xa0;cm [4–6]; overall p &lt; 0.001) and prior abscesses (49% vs. 16%, p = 0.013).</p> Conclusion <p>Management of CD-related abscesses varies by complexity. High rates of salvage treatment and delayed surgery underscore the need for tailored approaches.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Crohn’s Disease-Related Abdominal and Pelvic Abscesses: Treatment Patterns and Outcomes

  • 期刊论文

  • 发表日期：

    2026年2月19日

查看全文
  • Tarek Odah,
  • Farha Deceus,
  • Hani Tamim,
  • Francis A. Farraye,
  • Luca Stocchi,
  • Jana G. Hashash

摘要

Background

Abdominopelvic abscesses are significant complications in patients with Crohn’s disease (CD), often necessitating individualized management approaches. This study evaluates real-world treatment patterns and outcomes of CD-related abdominopelvic abscesses.

Methods

This retrospective cohort study included adult patients with CD developing disease-related abdominopelvic abscesses between January 2017 and October 2021. Initial management was at the discretion of treating physicians and categorized as surgery, interventional radiology (IR)-guided procedures, or medical therapy. Patients were followed for 2 years. Primary outcomes included rates of salvage surgery and salvage IR-guided procedures, defined as additional unplanned treatment following the initial management approach. Secondary outcomes included any surgery within 2 years, including planned or delayed surgical intervention.

Results

A total of 93 patients were included. Initial management included surgery in 25 (27%), IR-guided procedures in 35 (38%), and medical therapy alone in 33 patients (35%). Surgery was required in 60% within 2 years and 69% within 3 years. No variables were significantly associated with the need for surgery at 2 years on multivariable analysis. Salvage treatment was most frequent in the medical therapy group (39%) followed by IR (26%). Initial surgery was associated with presence of multiple abscesses (≥ 3 in 28% vs. 9% IR 3% medical; overall p = 0.047), while IR-drainage was associated with larger abscesses (median 5.0 cm [4–6]; overall p < 0.001) and prior abscesses (49% vs. 16%, p = 0.013).

Conclusion

Management of CD-related abscesses varies by complexity. High rates of salvage treatment and delayed surgery underscore the need for tailored approaches.