Scholarlink

Purpose <p>Endoscopic full-thickness resection (EFTR) using full thickness resection device is used for removal of non-lifting or previously manipulated polyps. There is limited data regarding its efficacy for removal of colorectal submucosal invasive cancer (SMIC).</p> Methods <p>We conducted retrospective multicenter study on patients who underwent EFTR using full thickness resection device for suspected or biopsy proven colorectal cancer (CRC).</p> Results <p>Technical success was 100% and R0 resection rate was 85%. Overall, 6/20 were referred for surgery due to high risk features. Curative resection rate was 46.7% (7/15) in T1 CRC. Adverse events included 1 bleeding and 1 perforation, managed endoscopically and 1 bleeding and 2 post-polypectomy syndromes managed conservatively.</p> Conclusions <p>Our series provides the first multicenter experience on EFTR for resection of colorectal SMIC from the United States. Longitudinal data from large scale studies are required to validate our initial experience of EFTR for SMIC.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Efficacy of Endoscopic Full Thickness Resection Using the Full-Thickness Resection Device for Submucosal Invasive Colorectal Cancer: The First United States Multicenter Experience

  • 期刊论文

  • 发表日期：

    2025年10月27日

查看全文
  • Rahul Karna,
  • Syed Kashif Mahmood,
  • Jennifer Phan,
  • Sumant Inamdar,
  • Antonio Mendoza Ladd,
  • Veeral M. Oza,
  • Mohit Girotra,
  • Harshit Khara,
  • Natalie Wilson,
  • Nabeel Azeem,
  • Mohammad Bilal

摘要

Purpose

Endoscopic full-thickness resection (EFTR) using full thickness resection device is used for removal of non-lifting or previously manipulated polyps. There is limited data regarding its efficacy for removal of colorectal submucosal invasive cancer (SMIC).

Methods

We conducted retrospective multicenter study on patients who underwent EFTR using full thickness resection device for suspected or biopsy proven colorectal cancer (CRC).

Results

Technical success was 100% and R0 resection rate was 85%. Overall, 6/20 were referred for surgery due to high risk features. Curative resection rate was 46.7% (7/15) in T1 CRC. Adverse events included 1 bleeding and 1 perforation, managed endoscopically and 1 bleeding and 2 post-polypectomy syndromes managed conservatively.

Conclusions

Our series provides the first multicenter experience on EFTR for resection of colorectal SMIC from the United States. Longitudinal data from large scale studies are required to validate our initial experience of EFTR for SMIC.