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Background <p>Pancreatic fluid collections (PFCs) are a frequent complication following acute pancreatitis and often necessitate endoscopic cystogastrostomy (EC) for drainage. Despite high technical and clinical success rates, unplanned readmissions remain common.</p> Aims <p>This study aimed to evaluate readmission rates and identify associated risk factors in patients undergoing EC for PFCs.</p> Methods <p>We conducted a retrospective review of 100 patients who underwent EC for symptomatic PFCs between June 2016 and August 2021. Demographic data, clinical characteristics, procedural details, and outcomes were analyzed. Univariate and multivariate logistic regression were used to identify factors associated with unplanned readmissions.</p> Results <p>Clinical success was achieved in 95% of patients. However, 31% experienced unplanned readmissions, most commonly due to sepsis (47%), abdominal pain (28%), and gastrointestinal bleeding (14%). Univariate analysis identified intra-abdominal varices and paracolic gutter extension as significant risk factors. Multivariate analysis confirmed intra-abdominal varices as an independent predictor (OR 3.51, 95% CI 1.26–9.80, <i>P</i> = 0.016). Technical success was high (98%) with an overall adverse event rate of 14%.</p> Conclusion <p>Unplanned readmissions are common after EC for PFCs, with intra-abdominal varices emerging as a key risk factor. Enhanced follow-up and risk stratification may improve patient outcomes and reduce healthcare burden.</p>

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Risk Factors for Readmissions in Patients Undergoing Endoscopic Drainage for Peripancreatic Fluid Collections

  • 期刊论文

  • 发表日期：

    2025年9月20日

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  • Timothy Tyler Daugherty,
  • Renato Beas,
  • Luis Hernandez,
  • Mohamed Rajput,
  • Juan Reyes Genere

摘要

Background

Pancreatic fluid collections (PFCs) are a frequent complication following acute pancreatitis and often necessitate endoscopic cystogastrostomy (EC) for drainage. Despite high technical and clinical success rates, unplanned readmissions remain common.

Aims

This study aimed to evaluate readmission rates and identify associated risk factors in patients undergoing EC for PFCs.

Methods

We conducted a retrospective review of 100 patients who underwent EC for symptomatic PFCs between June 2016 and August 2021. Demographic data, clinical characteristics, procedural details, and outcomes were analyzed. Univariate and multivariate logistic regression were used to identify factors associated with unplanned readmissions.

Results

Clinical success was achieved in 95% of patients. However, 31% experienced unplanned readmissions, most commonly due to sepsis (47%), abdominal pain (28%), and gastrointestinal bleeding (14%). Univariate analysis identified intra-abdominal varices and paracolic gutter extension as significant risk factors. Multivariate analysis confirmed intra-abdominal varices as an independent predictor (OR 3.51, 95% CI 1.26–9.80, P = 0.016). Technical success was high (98%) with an overall adverse event rate of 14%.

Conclusion

Unplanned readmissions are common after EC for PFCs, with intra-abdominal varices emerging as a key risk factor. Enhanced follow-up and risk stratification may improve patient outcomes and reduce healthcare burden.