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Objective <p>Assessing the relationship of body mass index (BMI) on acute pancreatitis (AP) hospitalization in the United States (US).</p> Methods <p>The National Inpatient Sample utilized to capture normal weight, overweight, and obese AP hospitalization in the US during 2020 based on BMI. Patients, hospitalization characteristics, and outcomes were compared.</p> Results <p>In 2020, there were 53,000 (20%) obese, 3980 (2.6%) overweight, and 210,000 (77.4%) normal weight AP hospitalizations. All-cause inpatient mortality was similar for obese, and overweight compared to normal weight AP hospitalizations, respectively (0.65% vs 0.63% vs 0.6%). Furthermore, obese AP hospitalization had a higher chance of developing systemic [odds ratio (OR): 1.7, confidence interval (CI) (1.35–2.12)], and needing intubation or vasopressor requirement OR: 1.75, CI (1.14–2.68), compared to normal AP patients. However, overweight AP hospitalizations had similar chance of developing systemic OR: 1.1, CI (0.83–1.38) and local complication OR: 1.14, CI (0.88–1.5), needing intubation or vasopressor requirements OR: 1.27, CI (0.73–2.23) except use of jejunostomy tube was higher OR: 1.74, CI (1.1–2.75) compared to normal weight AP hospitalizations. The mean length-of-stay and mean total healthcare costs were higher among obese by 2.14&#xa0;days (CI 0.9–3.37), <i>p</i> = 0.001 and by US$ 21,626, CI (4379–38,872), <i>p</i> = 0.014 compared to normal weight AP hospitalizations.</p> Conclusions <p>Obese and overnight AP hospitalizations had similar inpatient mortality compared to normal weight hospitalizations. Obese AP hospitalizations have higher complications and healthcare utilization compared to normal weight hospitalizations.</p>

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Outcomes of Acute Pancreatitis Hospitalizations with Obesity

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年2月13日

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  • Neelam Khetpal,
  • Mohamad Sharbatji,
  • Mohammad Maysara Asfari,
  • Sarfraz Ahmad

摘要

Objective

Assessing the relationship of body mass index (BMI) on acute pancreatitis (AP) hospitalization in the United States (US).

Methods

The National Inpatient Sample utilized to capture normal weight, overweight, and obese AP hospitalization in the US during 2020 based on BMI. Patients, hospitalization characteristics, and outcomes were compared.

Results

In 2020, there were 53,000 (20%) obese, 3980 (2.6%) overweight, and 210,000 (77.4%) normal weight AP hospitalizations. All-cause inpatient mortality was similar for obese, and overweight compared to normal weight AP hospitalizations, respectively (0.65% vs 0.63% vs 0.6%). Furthermore, obese AP hospitalization had a higher chance of developing systemic [odds ratio (OR): 1.7, confidence interval (CI) (1.35–2.12)], and needing intubation or vasopressor requirement OR: 1.75, CI (1.14–2.68), compared to normal AP patients. However, overweight AP hospitalizations had similar chance of developing systemic OR: 1.1, CI (0.83–1.38) and local complication OR: 1.14, CI (0.88–1.5), needing intubation or vasopressor requirements OR: 1.27, CI (0.73–2.23) except use of jejunostomy tube was higher OR: 1.74, CI (1.1–2.75) compared to normal weight AP hospitalizations. The mean length-of-stay and mean total healthcare costs were higher among obese by 2.14 days (CI 0.9–3.37), p = 0.001 and by US$ 21,626, CI (4379–38,872), p = 0.014 compared to normal weight AP hospitalizations.

Conclusions

Obese and overnight AP hospitalizations had similar inpatient mortality compared to normal weight hospitalizations. Obese AP hospitalizations have higher complications and healthcare utilization compared to normal weight hospitalizations.