EoE Recurrence on PPI Maintenance Therapy: You Do Not Know if You Do Not Look!

期刊论文
发表日期：

2024年10月15日

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Ryan Alexander,
Blake Kassmeyer,
Ryan Lennon,
Jeffrey Alexander,
Diana Snyder,
Karthik Ravi

摘要

Background and Aims

Data regarding histologic recurrence of EoE on PPI maintenance therapy are lacking.

Methods

Retrospective review of 101 patients with histologic PPI-responsive EoE.

Results

52/101 (51%) patients underwent follow-up EGD with biopsies. Of the 52 patients, 29 (56%) maintained histologic remission and 23 (44%) had histologic recurrence. 21 (40%) patients maintained BID PPI, 20 (39%) tapered to QD, and 11 (21%) had discontinued PPI. Of the 21 patients on BID PPI, 7 (33%) had histologic recurrence, of which 6 (86%) were asymptomatic.

Conclusions

Patients on PPI therapy for EoE benefit from serial clinical, endoscopic, and histologic surveillance.