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Feel the Burn: RFA for Chronic Radiation Proctitis

  • Gabriele De Sena,
  • Federico Maria Mongardini,
  • Danilo Porpora,
  • Maria Mauro,
  • Davide Bentivoglio,
  • Davide Centore,
  • Luigi Brusciano,
  • Claudio Gambardella,
  • Augusto Lauro,
  • Ludovico Docimo,
  • Vincenzo Napolitano

摘要

Chronic radiation proctitis, although relatively rare, can be the source of severe comorbidity in patients who had undergone prior radiotherapy for pelvic malignancy. Although current treatments for radiation proctitis include argon plasma coagulation, heater probe, bipolar neodymium/yttrium aluminum garnet (Nd: YAG) lasers, these interventions are often burdened by the frequent occurrence of rectal ulcerations and stenosis. Since radiofrequency ablation (RFA) is frequently used to ablate esophageal malignancy and pre-malignancy, we report the efficacy of RFA using through the scope system in two patients with rectal bleeding due to radiation proctitis. In both cases, the procedure was well-tolerated with hemostasis achieved after 1 or 2 sessions of RFA. Mucosal re-epithelialization was observed in areas of previous bleeding with no stenosis or ulceration observed at follow-up.