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Purpose <p>While intolerance of uncertainty (IU) is recognized as a contributing factor in obsessive-compulsive disorder (OCD), further research is needed to elucidate the underlying mechanisms linking these constructs. Specifically, the roles of beliefs regarding loss of control, transdiagnostic coping response styles [such as repetitive negative thinking (RNT) and depressive rumination], and OCD-specific coping mechanisms (e.g., experiential avoidance and mental rituals focused on intrusive thoughts) within this relationship remain unclear and warrant investigation.</p> Methods <p>This research evaluated the direct and indirect associations of IU with OCD symptoms by exploring potential mediating mechanisms in a large, clinically diagnosed OCD sample (<i>n</i> = 408). Participants completed both self-report questionnaires and clinician-administered interviews.</p> Results <p>IU demonstrates an indirect effect on OCD symptom, independent of comorbid conditions. This relationship was fully mediated by maladaptive beliefs concerning loss of control, a transdiagnostic coping (e.g., depressive rumination, but not though the RNT), and OCD-coping strategies, including experiential avoidance and mental rituals directed at intrusive thoughts.</p> Conclusion <p>This study highlights that the interplay between IU and OCD symptoms depends on the degree to which people with OCD exhibit a fear of losing control and engage in transdiagnostic response styles (e.g., depressive rumination) and coping methods revolving around intrusive thoughts in the context of OCD. Consequently, interventions aimed at reducing IU in the context of OCD symptoms should target beliefs concerning loss of control and both transdiagnostic and obsession-specific coping strategies.</p>

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How is Being Uncertain Linked to OCD Symptoms? Do Beliefs About Losing Control and Transdiagnostic and Disorder-Specific Coping Responses Matter?

  • 期刊论文

  • 发表日期：

    2025年5月31日

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  • Vahid Khosravani,
  • Seyed Mehdi Samimi Ardestani,
  • Richard Moulding,
  • Sajjad Amirpour,
  • Zeinab Pazhoohesh,
  • Morteza Aghaeimazraji,
  • Azra Mohammadpanah Ardakan

摘要

Purpose

While intolerance of uncertainty (IU) is recognized as a contributing factor in obsessive-compulsive disorder (OCD), further research is needed to elucidate the underlying mechanisms linking these constructs. Specifically, the roles of beliefs regarding loss of control, transdiagnostic coping response styles [such as repetitive negative thinking (RNT) and depressive rumination], and OCD-specific coping mechanisms (e.g., experiential avoidance and mental rituals focused on intrusive thoughts) within this relationship remain unclear and warrant investigation.

Methods

This research evaluated the direct and indirect associations of IU with OCD symptoms by exploring potential mediating mechanisms in a large, clinically diagnosed OCD sample (n = 408). Participants completed both self-report questionnaires and clinician-administered interviews.

Results

IU demonstrates an indirect effect on OCD symptom, independent of comorbid conditions. This relationship was fully mediated by maladaptive beliefs concerning loss of control, a transdiagnostic coping (e.g., depressive rumination, but not though the RNT), and OCD-coping strategies, including experiential avoidance and mental rituals directed at intrusive thoughts.

Conclusion

This study highlights that the interplay between IU and OCD symptoms depends on the degree to which people with OCD exhibit a fear of losing control and engage in transdiagnostic response styles (e.g., depressive rumination) and coping methods revolving around intrusive thoughts in the context of OCD. Consequently, interventions aimed at reducing IU in the context of OCD symptoms should target beliefs concerning loss of control and both transdiagnostic and obsession-specific coping strategies.