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<p>A new 20,28-epoxyursan triterpenoid (<b>1</b>), together with four known triterpenoids (<b>2–5</b>) were isolated from the ethanolic extract of the whole plants of <i>Potentilla nivea</i>. Their structures were elucidated on the basis of extensive spectroscopic and MS data analyses and comparing data reported. Among the isolates, compounds <b>1</b> and <b>5</b> showed potent inhibition with IC<sub>50</sub> values of 21.89 ± 0.40 and 27.99 ± 0.41 μM, respectively, against LPS-induced NO generation.</p>

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Triterpenoids from Potentilla nivea and Their Anti-Inflammatory Activities

  • 期刊论文

  • 发表日期：

    2026年6月18日

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  • Qiang Wu,
  • Xun Yan,
  • En Yuan,
  • Jing Wu,
  • Ling-Yun Zhong,
  • Yan-Ping Gao

摘要

A new 20,28-epoxyursan triterpenoid (1), together with four known triterpenoids (2–5) were isolated from the ethanolic extract of the whole plants of Potentilla nivea. Their structures were elucidated on the basis of extensive spectroscopic and MS data analyses and comparing data reported. Among the isolates, compounds 1 and 5 showed potent inhibition with IC50 values of 21.89 ± 0.40 and 27.99 ± 0.41 μM, respectively, against LPS-induced NO generation.