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<p>Two new ketone compounds, a new anthraquinone, 1,6-dihydroxy-2,7,8-trimethoxy-3-methylanthracene-9,10-dione (<b>1</b>) and one chromone, (S)-5-hydroxy-7-(hydroxymethyl)-2-(2-hydroxypropyl)-4H-chromen-4-one (<b>2</b>), along with two known flavonoids 3,3′,5′,5,7-pentahydroxyflavanone (<b>3</b>) and fisetinediol (<b>4</b>), were isolated from <i>Desmodium caudatum</i> (Thunb.) DC. and their structures were elucidated by spectroscopic methods. Compounds <b>1</b> and <b>2</b> were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds <b>1</b> and <b>2</b> showed anti-TMV activity with inhibition rates of 15.8 and 17.0%, respectively.</p>

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Two New Ketone Compounds with Anti-TMV Activity from Desmodium caudatum

  • 期刊论文

  • 发表日期：

    2026年3月1日

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  • Miao Dong,
  • Xiaojie Wang,
  • Qing-yang Wu,
  • Chao-ren Yu,
  • Ao-pin Yang,
  • Ru Huang,
  • Yin-ke Li

摘要

Two new ketone compounds, a new anthraquinone, 1,6-dihydroxy-2,7,8-trimethoxy-3-methylanthracene-9,10-dione (1) and one chromone, (S)-5-hydroxy-7-(hydroxymethyl)-2-(2-hydroxypropyl)-4H-chromen-4-one (2), along with two known flavonoids 3,3′,5′,5,7-pentahydroxyflavanone (3) and fisetinediol (4), were isolated from Desmodium caudatum (Thunb.) DC. and their structures were elucidated by spectroscopic methods. Compounds 1 and 2 were tested for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compounds 1 and 2 showed anti-TMV activity with inhibition rates of 15.8 and 17.0%, respectively.