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<p>The new indole alkaloid 12-hydroxydehydrotubifoline (<b>1</b>) containing the polycyclic akuammicine framework was isolated from <i>Vinca erecta</i>. Alkylation products of the major alkaloid 12-hydroxynorfluorocurarine with various alkyl halides were obtained. The structures of the new alkaloid 12-hydroxydehydrotubifoline and alkyl derivatives of 12-hydroxynorfluorocurarine were established by X-ray crystal structure analyses. Physicochemical and UV, IR, and NMR spectroscopic data of the obtained new compound were reported.</p>

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Structure of a New Indole Alkaloid from Vinca erecta and Alkyl Derivatives of 12-Hydroxynorfluorocurarine

  • 期刊论文

  • 发表日期：

    2026年1月1日

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  • Sh. M. Adizov,
  • O. Blacque,
  • B. Spingler,
  • B. Tashkhodzhaev

摘要

The new indole alkaloid 12-hydroxydehydrotubifoline (1) containing the polycyclic akuammicine framework was isolated from Vinca erecta. Alkylation products of the major alkaloid 12-hydroxynorfluorocurarine with various alkyl halides were obtained. The structures of the new alkaloid 12-hydroxydehydrotubifoline and alkyl derivatives of 12-hydroxynorfluorocurarine were established by X-ray crystal structure analyses. Physicochemical and UV, IR, and NMR spectroscopic data of the obtained new compound were reported.