<p>Known flavones <b>3–14</b> and two new flavone O-glycosides <b>1</b> and <b>2</b> were observed in herb of <i>Mentha</i> × <i>piperita</i> L. (Lamiaceae). The new flavonoids were 6-hydroxychrysoeriol 7-<i>O</i>-(6″-<i>O</i>-<i>α</i>-L-rhamnopyranosyl)-<i>β</i>-D-glucopyranoside (menthiside A, <b>1</b>) and chrysoeriol 7-<i>O</i>-(4″-<i>O-α</i>-L-rhamnopyranosyl)-<i>β</i>-D-glucopyranoside (menthiside B, <b>2</b>) according to UV and NMR spectroscopic and mass spectrometric data. Compounds <b>1</b> and <b>2</b> possessed the capability to inhibit the activity of soluble epoxide hydrolase (sEH).</p>

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New Flavone O-Glycosides from Mentha × piperita

  • D. N. Olennikov,
  • E. E. Kurdyukov

摘要

Known flavones 3–14 and two new flavone O-glycosides 1 and 2 were observed in herb of Mentha × piperita L. (Lamiaceae). The new flavonoids were 6-hydroxychrysoeriol 7-O-(6″-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside (menthiside A, 1) and chrysoeriol 7-O-(4″-O-α-L-rhamnopyranosyl)-β-D-glucopyranoside (menthiside B, 2) according to UV and NMR spectroscopic and mass spectrometric data. Compounds 1 and 2 possessed the capability to inhibit the activity of soluble epoxide hydrolase (sEH).