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<p>A new dimeric chromanone (<b>1</b>), together with ten known compounds (<b>2–11</b>), was isolated from the endophytic fungus <i>Pleospora</i> sp. BMX18 derived from healthy branches of <i>Aquilaria sinensis</i>. The structure of the new compound (<b>1</b>) was elucidated by extensive spectroscopic analyses, including high-resolution electron spray ionization mass spectrometry and nuclear magnetic resonance. Its absolute structure was assigned by analysis of CD spectrum. Compounds <b>8</b>, <b>10</b>, and <b>11</b> showed moderate antibacterial activities against <i>Aeromonas hydrophila, Vibrio owensii, Vibrio alginolyticus,</i> and <i>Aeromonas veronii.</i></p>

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A New Dimeric Chromanone from the Endophytic Fungus Pleospora sp. BMX18 Isolated from Aquilaria sinensis

  • 期刊论文

  • 发表日期：

    2025年11月19日

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  • Xin Luo,
  • Qing-Yun Ma,
  • Li Yang,
  • Qing-Yi Xie,
  • Jiao-Cen Guo,
  • Hao-Fu Dai,
  • Yan Hua,
  • You-Xing Zhao

摘要

A new dimeric chromanone (1), together with ten known compounds (2–11), was isolated from the endophytic fungus Pleospora sp. BMX18 derived from healthy branches of Aquilaria sinensis. The structure of the new compound (1) was elucidated by extensive spectroscopic analyses, including high-resolution electron spray ionization mass spectrometry and nuclear magnetic resonance. Its absolute structure was assigned by analysis of CD spectrum. Compounds 8, 10, and 11 showed moderate antibacterial activities against Aeromonas hydrophila, Vibrio owensii, Vibrio alginolyticus, and Aeromonas veronii.