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<p>A new tetraazacyclododecane, 2-nonyl-1,4,7,10-tetraazacyclododecane (<b>1</b>), along with nine isoquinoline alkaloids, northalifoline (<b>2</b>), thalifoline (<b>3</b>), corydaldine (<b>4</b>), N-methylcorydaldine (<b>5</b>), oxyberberine (<b>6</b>), berberine (<b>7</b>), palmatine (<b>8</b>), jatrorrhizine (<b>9</b>), and columbamine (<b>10</b>) were isolated from the bark of <i>Ilex latifolia</i> (Aquifoliaceae). The structure of the new tetraazacyclododecane was elucidated by chemical and physical evidence.</p>

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A New Tetraazacyclododecane of Ilex latifolia

  • 期刊论文

  • 发表日期：

    2025年9月18日

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  • C. T. Chang,
  • C. L. Kao,
  • S. T. Huang,
  • M. J. Cheng,
  • C. Y. Chen,
  • H. T. Li

摘要

A new tetraazacyclododecane, 2-nonyl-1,4,7,10-tetraazacyclododecane (1), along with nine isoquinoline alkaloids, northalifoline (2), thalifoline (3), corydaldine (4), N-methylcorydaldine (5), oxyberberine (6), berberine (7), palmatine (8), jatrorrhizine (9), and columbamine (10) were isolated from the bark of Ilex latifolia (Aquifoliaceae). The structure of the new tetraazacyclododecane was elucidated by chemical and physical evidence.