<p>A new pyridine, 4-(1′-hydroxy-2′-methylpropyl)pyridine-2-carboxylic acid (<b>16</b>), along with fifteen known compounds including α-humulene (<b>1</b>), zerumbone (<b>2</b>), zerumbone epoxide (<b>3</b>), <i>β</i>-sitosterone (<b>4</b>), <i>β</i>-sitosterol (<b>5</b>), kaempferol-3-O-(3′′,4′′-O-diacetyl)rhamnoside (<b>6</b>), kaempferol-3-O-(4′′-O-acetyl)rhamnoside, kaempferol-3,4′-O-dimethylether (<b>8</b>), ferulic acid (<b>9</b>), vanillic acid (<b>10</b>), methyl indole-3-carboxylate (<b>11</b>), indole-3-carbaldehyde (<b>12</b>), indole-3-carboxylic acid (<b>13</b>), pyridine-2-carboxylic acid (picolinic acid) (<b>14</b>), and 3-methylpyridine-2-carboxylic acid (3-methylpicolinic acid) (<b>15</b>) were isolated from the rhizomes of <i>Zingiber zerumbet</i> (L.) Sm. (Zingiberaceae). The structure of the new pyridine was elucidated by physical evidence.</p>

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Metabolites from Zingiber zerumbet with Antioxidant Activity

  • C. Y. Chen,
  • C. L. Kao,
  • H. T. Li,
  • S. T. Huang,
  • W. J. Li

摘要

A new pyridine, 4-(1′-hydroxy-2′-methylpropyl)pyridine-2-carboxylic acid (16), along with fifteen known compounds including α-humulene (1), zerumbone (2), zerumbone epoxide (3), β-sitosterone (4), β-sitosterol (5), kaempferol-3-O-(3′′,4′′-O-diacetyl)rhamnoside (6), kaempferol-3-O-(4′′-O-acetyl)rhamnoside, kaempferol-3,4′-O-dimethylether (8), ferulic acid (9), vanillic acid (10), methyl indole-3-carboxylate (11), indole-3-carbaldehyde (12), indole-3-carboxylic acid (13), pyridine-2-carboxylic acid (picolinic acid) (14), and 3-methylpyridine-2-carboxylic acid (3-methylpicolinic acid) (15) were isolated from the rhizomes of Zingiber zerumbet (L.) Sm. (Zingiberaceae). The structure of the new pyridine was elucidated by physical evidence.