<p>The syntheses of new potentially biologically active derivatives of ursolic and corosolic acids containing terminal aminoguanidinium and biguanidinium groups in a C-28 side chain bonded to the triterpene core by some linear alkane and tri(ethylene glycol) linkers or a branched tris(aminoethyl)amine moiety are described.</p>

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Synthesis of New Carboxamide Derivatives of Ursolic and Corosolic Acids with Terminal Guanidinium and Biguanidinium Groups in a C-28 Side Chain

  • A. Yu. Spivak,
  • R. R. Khalitova,
  • D. A. Nedopekina,
  • E. V. Davletshin

摘要

The syntheses of new potentially biologically active derivatives of ursolic and corosolic acids containing terminal aminoguanidinium and biguanidinium groups in a C-28 side chain bonded to the triterpene core by some linear alkane and tri(ethylene glycol) linkers or a branched tris(aminoethyl)amine moiety are described.