Scholarlink

<p>A new tetraphenylene, named 6-(3′,4′-dihydroxy-5-methyl-[1,1′-biphenyl]-3-yl)-2,5-dihydroxybenzofuran-7-yl 2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoate (<b>1</b>), and seven known biphenyl derivatives (<b>2–8</b>) were isolated from <i>Cucumis bisexualis</i> for the first time. The structures of compounds <b>(1–8</b>) were determined by their spectral data and related references. Compounds (<b>1–8</b>) were evaluated for their hepatoprotective activities against D-galactosamine-induced toxicity in HL-7702 cells, with bicyclol as a positive control. As a result, compounds <b>1</b>, <b>2</b>, and <b>4</b> displayed moderate hepatoprotective activities.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Hepatoprotective Biphenyl Derivatives from Cucumis bisexualis

  • 期刊论文

  • 发表日期：

    2025年1月1日

查看全文
  • Qinge Ma,
  • Wenmin Liu,
  • Zhipei Sang,
  • Rongrui Wei

摘要

A new tetraphenylene, named 6-(3′,4′-dihydroxy-5-methyl-[1,1′-biphenyl]-3-yl)-2,5-dihydroxybenzofuran-7-yl 2,4-dihydroxy-3-(3-methylbut-2-en-1-yl)benzoate (1), and seven known biphenyl derivatives (2–8) were isolated from Cucumis bisexualis for the first time. The structures of compounds (1–8) were determined by their spectral data and related references. Compounds (1–8) were evaluated for their hepatoprotective activities against D-galactosamine-induced toxicity in HL-7702 cells, with bicyclol as a positive control. As a result, compounds 1, 2, and 4 displayed moderate hepatoprotective activities.