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Acylation of Azepanoglycyrrhetol

  • A. V. Terekhova,
  • A. V. Petrova,
  • O. B. Kazakova,
  • Yu.V. Vakhitova,
  • D. N. Polovyanenko,
  • I. Yu. Bagryanskaya

摘要

Acylation of azepano-11-deoxoglycyrrhetol synthesized N-acetyl- and N,O-bis-acetyl derivatives. The structure of azepano-11-deoxoglycyrrhetol was confirmed by an XSA. Data for its influence on cell cycle progression suggested that suppression of cell survival was due primarily to a cytostatic effect that was related to arrest of the S or G1 phase, depending on the cell line.