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A New Lanostane-Type Triterpene from the Branches of Thai Uvaria siamensis

  • Ngoc-Hong Nguyen,
  • Boi-Phong Vuong,
  • Dinh-Manh Nguyen,
  • Thuc-Huy Duong,
  • Hoang-Thanh Kpa,
  • Thi-Kim-Dung Le,
  • Thi-Ngoc-Duyen Nguyen,
  • Huy Truong Nguyen,
  • Jirapast Sichaem

摘要

A new lanostane-type triterpene, uvariaol (1), was isolated from the branches of Thai Uvaria siamensis, along with three known compounds, polycarpol (2), fisetinidol (3), and stigmast-4-en-3-one (4). Their structures were elucidated through extensive spectroscopic analyses and comparison with existing literature. The α-glucosidase inhibitory potential of compounds 1–4 was evaluated. Compound 1 exhibited significant inhibitory activity against α-glucosidase, surpassing the potency of the positive control, with an IC50 value of 30.8 ± 1.5 μM.