New Metabolites of Rhodiola rosea. III. Glycosides of Hydroquinone, Tyrosol, and Rosiridol

The water-soluble part of the EtOH extract of Rhodiola rosea L. [Sedum roseum (L.) Scop., Crassulaceae] contained 15 compounds including six new glycosides 1–6. UV and NMR spectroscopic and mass spectrometric data and chemical transformations determined the structures of the new compounds as hydroquinone 1-O-(6′-O-α-L-arabinopyranosyl)-β-D-glucopyranoside (rhodirosin I, 1), hydroquinone 1-O-(6′-O-α-Larabinofuranosyl)-β-D-glucopyranoside (rhodirosin J, 2), tyrosol 1-O-(6′-O-α-L-arabinofuranosyl)-β-Dglucopyranoside (rhodirosin K, 3), tyrosol 1-O-(2′-O-acetyl)-β-D-glucopyranoside (rhodirosin L, 4), tyrosol 1-O-(2′,6′-di-O-acetyl)-β-D-glucopyranoside (rhodirosin M, 5), and rosiridol 1-O-(2′,6′-di-O-acetyl)-β-D-glucopyranoside (rhodirosin N, 6).