Two New Inositol Compounds with Bacteriostatic Activity from Thalictrum scabrifolium var. leve in Heqing
摘要
Two new inositol compounds, myoinositol-1,3-di-4-hydroxybenzoyl-2-methylbutyrate (1) and myoinositol-1,3-di-4-hydroxybenzoyl-2-isobutyrate (2), along with two known ones, were isolated from Thalictrum scabrifolium var. leve Franch., and their structures were elucidated by spectroscopic methods. Compounds 1 and 2 exhibited activities to inhibit Staphylococcus epidermidis with an MIC of 5.00 mg/mL and 4.50 mg/mL at a concentration of 5 mg/mL. Moreover, they had a certain inhibitory effect on Escherichia coli and Staphylococcus aureus.