Synthesis of condensed furan structures based on 1-aryl-3-bromo-3-nitropropenones
摘要
This study presents an efficient method for the synthesis of condensed 3-aroyl-containing furan heterocycles, which are notable for their diverse biological activity, including antibacterial, antifungal, anti-inflammatory, and anticancer. The proposed method involves reaction of 1-aryl-3-bromo-3-nitropropenones with cyclic CH acids, yielding 3-aroyldihydrobenzofuran-4(5H)-ones and 3-aroyl-4H-furo[3,2-c]- chromen-4-ones in excellent yields, providing a valuable approach for developing new biologically active compounds.