Visible-light-induced Ir-catalyzed site-selective C−H trifluoromethylation of 3-substituted 1,2-benzoxazoles
摘要
A new protocol for visible-light-induced C–H trifluoromethylation at C-4 position of 1,2-benzoxazoles has been disclosed with Togni reagent II at room temperature in the presence of fac-Ir(ppy)3. This approach features simple operation, high efficiency, and specific selectivity.