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A one-pot synthesis of 3-nitro-2H-thiopyrans and their selective reduction to 3-nitro-3,4-dihydro-2H-thiopyrans

  • Ivan D. Karpov,
  • Aleksei V. Kolobov,
  • Ilya P. Filippov,
  • Nikolai V. Rostovskii,
  • Konstantin L. Ovchinnikov

摘要

A one-pot method for the synthesis of 3-nitro-2H-thiopyrans starting from enamin-3-ones was developed. Reduction of the obtained 3-nitro-2H-thiopyrans with the benzaldehyde/o-phenylenediamine system in butanol led to 3-nitro-3,4-dihydro-2H-thiopyrans.