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A method for the synthesis of spiro-1,3,4-thiadiazolines

  • Alexander V. Komkov,
  • Leonid G. Menchikov,
  • Andrey S. Dmitrenok,
  • Natalya G. Kolotyrkina,
  • Igor V. Zavarzin

摘要

A method for the synthesis of spiro-1,3,4-thiadiazolines by the reaction of cyclic ketones with oxamic acid thiohydrazides was developed. A number of new nonsteroidal spiro-1,3,4-thiadiazolines was obtained in high yields.