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<p>Healthcare-Associated Infections (HAIs) pose a critical threat to patient safety and public health. Conventional antimicrobial agents, along with their synthesis and application to textiles, have notable limitations. This study investigates the antibacterial efficacy of selenium nanoparticle (SeNP) coatings deposited on textiles via ultrasonic spray coating for the development of infection-resistant fabrics. The effects of selenium precursor concentration, ascorbic acid concentration, PVP concentration, and PVP molecular weight were examined on the synthesis and stability of selenium nanoparticles. Ultrasonic spray coating was applied to diverse textile substrates. Lower molecular weight PVP produced smaller, monodisperse SeNPs (∼66&#xa0;nm), whereas higher molecular weight PVP led to aggregation and the formation of larger particles. Increased PVP concentration also caused aggregation and larger particles, even when low molecular weight PVP was used. Ascorbic acid alone was insufficient to provide adequate stability to selenium nanoparticles. XRD analysis confirmed the formation of nanocrystalline trigonal selenium in the synthesized nanoparticles. Characterization by FTIR, SEM, and EDS confirmed conformal coating that preserved fabric porosity while verifying selenium deposition. Antibacterial testing against <i>Staphylococcus aureus</i> demonstrated effective antibacterial activity for all coated fabrics. Air permeability testing confirmed that the breathability of the coated fabrics was maintained. Although certain drawbacks remain, this study demonstrates the potential of ultrasonically deposited SeNP coatings in developing breathable, antimicrobial medical textiles.</p>

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Infection-resistant fabrics via spray deposition of selenium nanoparticles on cellulosic and synthetic fabrics

  • 期刊论文

  • 发表日期：

    2026年3月21日

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  • Awais Ahmed Khan,
  • Muhammad Irfan,
  • Amjed Javid

摘要

Healthcare-Associated Infections (HAIs) pose a critical threat to patient safety and public health. Conventional antimicrobial agents, along with their synthesis and application to textiles, have notable limitations. This study investigates the antibacterial efficacy of selenium nanoparticle (SeNP) coatings deposited on textiles via ultrasonic spray coating for the development of infection-resistant fabrics. The effects of selenium precursor concentration, ascorbic acid concentration, PVP concentration, and PVP molecular weight were examined on the synthesis and stability of selenium nanoparticles. Ultrasonic spray coating was applied to diverse textile substrates. Lower molecular weight PVP produced smaller, monodisperse SeNPs (∼66 nm), whereas higher molecular weight PVP led to aggregation and the formation of larger particles. Increased PVP concentration also caused aggregation and larger particles, even when low molecular weight PVP was used. Ascorbic acid alone was insufficient to provide adequate stability to selenium nanoparticles. XRD analysis confirmed the formation of nanocrystalline trigonal selenium in the synthesized nanoparticles. Characterization by FTIR, SEM, and EDS confirmed conformal coating that preserved fabric porosity while verifying selenium deposition. Antibacterial testing against Staphylococcus aureus demonstrated effective antibacterial activity for all coated fabrics. Air permeability testing confirmed that the breathability of the coated fabrics was maintained. Although certain drawbacks remain, this study demonstrates the potential of ultrasonically deposited SeNP coatings in developing breathable, antimicrobial medical textiles.