Scholarlink

<p>Globally, there is a significant concern about controlling the growth of pathogenic microorganisms to prevent infectious diseases. In this context, the study focused on the synthesis of a nanocomposite via the Ugi multicomponent reaction using silanized titanate nanotubes [NtsTi–Si(CH<sub>2</sub>)<sub>3</sub>NH<sub>2</sub>] and bacterial nanocellulose (BNC–COOH) with antimicrobial properties. The NtsTi–Si(CH<sub>2</sub>)<sub>3</sub>NH<sub>2</sub> exhibited antimicrobial activity, with inhibition halos of 21&#xa0;mm against <i>S. aureus</i> and 25&#xa0;mm against <i>E. coli</i>. Additionally, the [BNC–COOH/NtsTi–Si(CH<sub>2</sub>)<sub>3</sub>NH<sub>2</sub>] nanocomposite was tested against Gram-negative and Gram-positive bacteria, showing inhibition halos of 9&#xa0;mm against <i>E. coli</i> and 15&#xa0;mm against <i>S. aureus</i>, indicating sensitivity comparable to that of chloramphenicol.</p> Graphical abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Antibacterial properties of nanocomposites based on titanate nanotubes and bacterial nanocellulose functionalized through UGI reaction

  • 期刊论文

  • 发表日期：

    2025年2月20日

查看全文
  • Amanda Alves da Cruz,
  • Gustavo Henrique Couto,
  • Cristiane Pilissão

摘要

Globally, there is a significant concern about controlling the growth of pathogenic microorganisms to prevent infectious diseases. In this context, the study focused on the synthesis of a nanocomposite via the Ugi multicomponent reaction using silanized titanate nanotubes [NtsTi–Si(CH2)3NH2] and bacterial nanocellulose (BNC–COOH) with antimicrobial properties. The NtsTi–Si(CH2)3NH2 exhibited antimicrobial activity, with inhibition halos of 21 mm against S. aureus and 25 mm against E. coli. Additionally, the [BNC–COOH/NtsTi–Si(CH2)3NH2] nanocomposite was tested against Gram-negative and Gram-positive bacteria, showing inhibition halos of 9 mm against E. coli and 15 mm against S. aureus, indicating sensitivity comparable to that of chloramphenicol.

Graphical abstract