<p>The current review presents a survey on the recent developments in the field of magnetic nanocatalysts for efficient and green synthesis of the chromene-3-carbonitrile derivatives by multicomponent reactions. Different types of magnetic nanoparticles, such as Fe₃O₄-based cores which can be functionalized with silica, Schiff base complexes, metal dopants (Cu, Co, Mo, Pd), and bio-based supports (mica, agar, kaoline), have been designed to catalyze Knoevenagel condensation, then Michael addition and cyclization under mild, solvent-free or environmentally benign conditions. It is worth noting that the dendrimeric oxo-vanadium phthalocyanine, copper ferrite, molybdenum Schiff base complexes, and hybrid ZnS/CuFe₂O₄/agar systems are among the catalysts that are highly active, selective, and reusable, with the yields of most programs reaching over 90%. Green methods of synthesis through ultrasound radiation, natural support, and reduced biogenic agents are more sustainable. The catalysts that are reviewed possess easy magnetic separation and can be reused in numerous cycles with little loss in activity. All this combined highlights the future of magnetic nanocatalysts as future multi-purpose, eco-friendly catalysts to make biologically relevant chromene-3-carbonitrile analogs, with applications in pharmaceutical and industrial applications.</p>