<p>Water plays a crucial role in sustaining life on Earth, and the upheaving population and pollution have accelerated the contamination in natural water sources. The unique physicochemical properties of ferrite nanoparticles have shown promising, and potential activity extensively in wastewater treatment. These ferrite nanoparticles can be synthesized by harnessing a wide variety of methods to overcome the problem aroused by engaging with conventional techniques. Among them, green synthesis serves as an alternative solution, as it is biocompatible, low in toxicity, economically feasible, and utilizes natural products and their derivatives. This review provides a comprehensive overview of various synthesis methods for ferrite nanoparticles, including conventional and biomolecule-assisted techniques. Further, explored on the factors governing photocatalytic degradation, such as the particle’s physico-chemical properties, pH, catalyst dosage, and irradiation source. Also, highlights on several modifications—such as elemental doping and composite formation to increase its competence in photodegradation. It then shifts to identify and analyze the current challenges to practical deployment, and promising avenues of future research are identified. This includes outlining concrete directions that may help in the further development of scalable, stable, and eco-friendly ferrite-based photocatalysts. The ultimate goal of this forward-looking perspective is to facilitate translation of ferrite materials into real-world wastewater treatment applications that ensure both performance and environmental safety at scale.</p> Graphical Abstarct