Scholarlink

<p>The development of multifunctional and sustainable catalysts for heterocycle construction remains critically important in modern organic chemistry. A novel Zr/P co-doped TiO<sub>2</sub> nanocatalyst that was made via a Sol-gel chemical method and show how well it performs in the green, microwave-assisted production of azlactones. Zr and P co-doping creates oxygen vacancies, increases Lewis/Brønsted acidity, narrows the band gap, and greatly improves charge-carrier separation features directly responsible for the catalyst’s remarkable activity—in contrast to pristine TiO<sub>2</sub>, which has a wide band gap and rapid charge recombination. This material provides greater yields (89–96%), significantly shorter reaction durations (3–4&#xa0;min), and superior recyclability when compared to previously reported TiO<sub>2</sub> based or metal-oxide catalysts. Through quick dielectric heating, microwave irradiation speeds up reaction kinetics even more, creating a synergistic boost for azlactone synthesis that has never been seen before. Thus, this study presents a unique dual-strategy catalytic system that combines microwave activation and defect-engineered TiO<sub>2</sub> nanophotocatalysis, providing a scalable, energy-efficient, and environmentally friendly pathway to pharmaceutically relevant azlactones.</p> Graphical Abstract <p></p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Zr/P Co-Doped TiO2 Nanonanocatalyst for Microwave-Assisted Green Synthesis of Bioactive Azlactones: Enhanced Catalytic Performance and Mechanistic Insights

  • 期刊论文

  • 发表日期：

    2025年12月12日

查看全文
  • Lakshmi Rekha Buddiga,
  • Ganapathi Rao Gajula,
  • Manuri Brahmayya,
  • Ponnala Bhanuchander

摘要

The development of multifunctional and sustainable catalysts for heterocycle construction remains critically important in modern organic chemistry. A novel Zr/P co-doped TiO2 nanocatalyst that was made via a Sol-gel chemical method and show how well it performs in the green, microwave-assisted production of azlactones. Zr and P co-doping creates oxygen vacancies, increases Lewis/Brønsted acidity, narrows the band gap, and greatly improves charge-carrier separation features directly responsible for the catalyst’s remarkable activity—in contrast to pristine TiO2, which has a wide band gap and rapid charge recombination. This material provides greater yields (89–96%), significantly shorter reaction durations (3–4 min), and superior recyclability when compared to previously reported TiO2 based or metal-oxide catalysts. Through quick dielectric heating, microwave irradiation speeds up reaction kinetics even more, creating a synergistic boost for azlactone synthesis that has never been seen before. Thus, this study presents a unique dual-strategy catalytic system that combines microwave activation and defect-engineered TiO2 nanophotocatalysis, providing a scalable, energy-efficient, and environmentally friendly pathway to pharmaceutically relevant azlactones.

Graphical Abstract