Palladium-Based Catalyst on L-Histidine-Modified Boron Nitride Nanosheets: A Novel, Stable, and Highly Efficient Heterogeneous Catalyst for Suzuki–Miyaura Reaction

In this study, we developed a multiphase catalyst, BNNSs/His-Pd, by anchoring palladium nanoparticles onto L-histidine-modified boron nitride nanosheets. BNNSs/His-Pd was shown to be a good 2D heterogeneous catalyst. The enhanced affinity of the modified BNNSs for metal complexes, coupled with their inherent stability, contributes to the catalytic activity of the BNNSs/His-Pd-catalyzed Suzuki coupling reaction. The catalyst showed a broad substrate scope, good catalytic activity, and the convenience of not requiring inert gas protection in the Suzuki–Miyaura cross-coupling reaction. Even after 10 recycling cycles, the product yield remained at 95%, highlighting its significant potential for practical applications.

Stable and efficient BNNSs/His-Pd heterogeneous catalysts were successfully constructed by modifying boron nitride nanosheets with L-histidine. The effect of L-histidine enhanced the dispersion and stability of Pd NPs on BNNSs carriers, combined with the inherent stability of BNNSs which resulted in the improvement of catalytic activity and recycling performance of the catalysts in the Suzuki coupling reaction.