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<p>The transmissibility rate of the SARS-CoV-2 virus, which causes COVID-19, in organ and tissue donation is not known. Considering all issues related to the risk of SARS-CoV-2 transmission and the risk of tissue shortages due to donor exclusion, this in vitro study evaluated the detection of SARS-CoV-2 RNA in bone tissue models after bone processing for tissue bank. Bone processing has activity against SARS-CoV-2 and not RNA was detected in the end of the process. The use of bone tissue can be considered in case of shortage.</p>

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COVID-19 detection in bone tissue after a new protocol for decellularize bone with sustained collagen matrix

  • 期刊论文

  • 发表日期：

    2025年6月5日

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  • Leticia Ramos Dantas,
  • Felipe Francisco Tuon

摘要

The transmissibility rate of the SARS-CoV-2 virus, which causes COVID-19, in organ and tissue donation is not known. Considering all issues related to the risk of SARS-CoV-2 transmission and the risk of tissue shortages due to donor exclusion, this in vitro study evaluated the detection of SARS-CoV-2 RNA in bone tissue models after bone processing for tissue bank. Bone processing has activity against SARS-CoV-2 and not RNA was detected in the end of the process. The use of bone tissue can be considered in case of shortage.