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Purpose <p>Epicardial adipose tissue (EAT) modulates cardiovascular risk, but its surgical implications remain unclear. We investigated whether CT-quantified EAT predicts postoperative outcomes in isolated coronary artery bypass grafting (CABG) patients.</p> Methods <p>This retrospective study analysed isolated CABG patients (2017–2024) with preoperative CT. EAT volume and thickness were measured using semi-automated segmentation. Primary endpoints were correlation of EAT with postoperative clinical outcomes; sternal wound infection, renal insufficiency, cerebrovascular events, postoperative atrial fibrillation (POAF) and other cardiac arrhythmias, and short- and medium-term mortality.</p> Results <p>The study included 325 patients. EAT volume &gt; 108&#xa0;cm³ predicted sternal wound infection (AUC = 0.632, 62.5% sensitivity, 63.5% specificity; <i>p</i> = 0.0135). EAT thickness &gt; 30.5&#xa0;mm correlated with 30-day mortality (AUC = 0.650, <i>p</i> = 0.0428). No association with POAF was observed (<i>p</i> = 0.21).</p> Conclusions <p>Quantification of EAT in CABG patients may be a prognostic marker, especially providing risk assessment regarding postoperative sternal infection and short- term mortality.</p> Graphical abstract <p></p>

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The impact of epicardial adipose tissue quantification by computed tomography on predicting postoperative outcomes in coronary artery bypass grafting surgery

  • 期刊论文

  • 发表日期：

    2026年2月18日

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  • Mehmet Dogmus,
  • Sevtap Dogan,
  • Ozgur Baris,
  • Canbolat Mert Holat,
  • Mustafa Eren Tosun,
  • Torehan Ozer

摘要

Purpose

Epicardial adipose tissue (EAT) modulates cardiovascular risk, but its surgical implications remain unclear. We investigated whether CT-quantified EAT predicts postoperative outcomes in isolated coronary artery bypass grafting (CABG) patients.

Methods

This retrospective study analysed isolated CABG patients (2017–2024) with preoperative CT. EAT volume and thickness were measured using semi-automated segmentation. Primary endpoints were correlation of EAT with postoperative clinical outcomes; sternal wound infection, renal insufficiency, cerebrovascular events, postoperative atrial fibrillation (POAF) and other cardiac arrhythmias, and short- and medium-term mortality.

Results

The study included 325 patients. EAT volume > 108 cm³ predicted sternal wound infection (AUC = 0.632, 62.5% sensitivity, 63.5% specificity; p = 0.0135). EAT thickness > 30.5 mm correlated with 30-day mortality (AUC = 0.650, p = 0.0428). No association with POAF was observed (p = 0.21).

Conclusions

Quantification of EAT in CABG patients may be a prognostic marker, especially providing risk assessment regarding postoperative sternal infection and short- term mortality.

Graphical abstract