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<p>Recurrent pericarditis is an uncommon extraintestinal manifestation of inflammatory bowel disease and may arise from biologic-induced autoimmunity. Anti–tumor necrosis factor (TNF) agents such as infliximab can trigger drug-induced lupus, with pericardial involvement representing a rare presentation. Cardiac magnetic resonance (CMR) enables precise evaluation of pericardial inflammation, guiding treatment strategies and supporting safe immunomodulatory tapering.</p>

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Infliximab-induced lupus with recurrent pericarditis: longitudinal CMR assessment of inflammatory resolution

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2026年3月16日

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  • Vaidehi Mendpara,
  • Joseph El Roumi,
  • Allan Klein

摘要

Recurrent pericarditis is an uncommon extraintestinal manifestation of inflammatory bowel disease and may arise from biologic-induced autoimmunity. Anti–tumor necrosis factor (TNF) agents such as infliximab can trigger drug-induced lupus, with pericardial involvement representing a rare presentation. Cardiac magnetic resonance (CMR) enables precise evaluation of pericardial inflammation, guiding treatment strategies and supporting safe immunomodulatory tapering.