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<p>To assess the feasibility of a native 3D T1-weighted Bright-blood and black-blOOd phase SensiTive (BOOST) cardiac MRI sequence for detecting acute atrial lesions immediately after radiofrequency ablation (RFA), without gadolinium contrast administration. Ten atrial fibrillation patients underwent 3T cardiac MRI within one hour following RFA. Whole-heart black-blood T1-weighted BOOST and late gadolinium enhanced (LGE) images were acquired during free breathing. Two experienced readers independently assessed the presence and continuity of acute lesions in six predefined pulmonary vein (PV) antrum quadrants per patient. Findings were correlated with procedural RFA parameters. BOOST and LGE sequences detected high signal intensity lesions in all patients, involving both right and left PV antra. BOOST identified acute lesions in 62 and 63% of right and left PV quadrants, respectively, against 100% of quadrants with LGE. Over 80% of LGE-positive quadrants also showed microvascular obstruction. Quadrants with absent or discontinuous BOOST lesions were associated with a significantly greater inter-lesion distance and lower impedance drop during RFA compared to quadrants with continuous lesions. Whole-heart black-blood T1-weighted BOOST cardiac MRI at 3T enables detection of acute PV antrum lesions immediately after RFA without contrast administration. This contrast-free imaging technique may enable real-time, gadolinium-free lesion assessment during or immediately after RFA.</p> Graphical abstract <p></p>

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Non-contrast 3D T1-weighted MRI at 3T for early detection of atrial lesions post-ablation in atrial fibrillation: a pilot study

  • 期刊论文

  • 发表日期：

    2026年1月27日

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  • Jean-François Deux,
  • Miklos Kassai,
  • Nicolas Johner,
  • Carl Glessgen,
  • Lindsey Alexandra Crowe,
  • Karl-Philipp Kunze,
  • René Michael Botnar,
  • Claudia Prieto,
  • Dipen Shah,
  • Jean-Paul Vallée

摘要

To assess the feasibility of a native 3D T1-weighted Bright-blood and black-blOOd phase SensiTive (BOOST) cardiac MRI sequence for detecting acute atrial lesions immediately after radiofrequency ablation (RFA), without gadolinium contrast administration. Ten atrial fibrillation patients underwent 3T cardiac MRI within one hour following RFA. Whole-heart black-blood T1-weighted BOOST and late gadolinium enhanced (LGE) images were acquired during free breathing. Two experienced readers independently assessed the presence and continuity of acute lesions in six predefined pulmonary vein (PV) antrum quadrants per patient. Findings were correlated with procedural RFA parameters. BOOST and LGE sequences detected high signal intensity lesions in all patients, involving both right and left PV antra. BOOST identified acute lesions in 62 and 63% of right and left PV quadrants, respectively, against 100% of quadrants with LGE. Over 80% of LGE-positive quadrants also showed microvascular obstruction. Quadrants with absent or discontinuous BOOST lesions were associated with a significantly greater inter-lesion distance and lower impedance drop during RFA compared to quadrants with continuous lesions. Whole-heart black-blood T1-weighted BOOST cardiac MRI at 3T enables detection of acute PV antrum lesions immediately after RFA without contrast administration. This contrast-free imaging technique may enable real-time, gadolinium-free lesion assessment during or immediately after RFA.

Graphical abstract