Scholarlink

<p>Rotation of the aortic root (AoR) has previously been observed in children with Tetralogy of Fallot (TOF) using 2-dimensional echocardiography. The present study uses cardiovascular magnetic resonance (CMR) imaging to assess whether a clockwise AoR rotation is a common feature in adults with TOF. AoR rotation was measured in the CMR images of consecutive adult patients with corrected TOF and controls. The AoR rotation was assessed in the parasternal short-axis view by measuring the angle of the non-coronary sinus (angle NCS) relative to the interatrial septum (IAS). The angle between IAS and posterior atrial wall was measured to asses IAS reliability as a key anatomical landmark. Inter-observer agreement was determined using intra-class correlation coefficients (ICC). A total of 25 adults with TOF (mean age:33.2 ± 13.1 years;52% male) and 30 controls (mean age:54.5 ± 19.0 years;50% male) were assessed. The angle NCS was greater in TOF patients than in controls (46.2 ± 17.1⁰vs.23.4 ± 15.0⁰, <i>p</i> &lt; 0.001), reflecting a clockwise AoR rotation. As expected, between TOF patients and controls there was no significant difference in the angle IAS (81.1 ± 8.4⁰vs.78.4 ± 9.5⁰, <i>p</i> = 0.46). Inter-observer reliability of CMR measurements was good for the clinically important angle NCS (ICC 0.77, 95%-CI:0.63–0.86) and moderate for the angle IAS (ICC 0.68, 95%-CI:0.51–0.80). This is the first study to demonstrate with CMR that a clockwise rotation of the AoR is a common feature in patients with TOF. This clinical investigation shows the value of CMR for the assessment of the spatial AoR position in adult patients with congenital heart disease.</p>

错误：搜索内容不能为空，请输入英文关键词
错误：关键词超出字数限制，请精简
高级检索

Clockwise aortic root rotation in patients with tetralogy of fallot assessed with cardiovascular magnetic resonance imaging

  • 期刊论文

  • 出版模式：

    开放获取

  • 发表日期：

    2025年6月23日

查看全文
  • Marco Voortman,
  • Jan van Es,
  • Clemens von Birgelen,
  • Eline H. Ploumen,
  • Carine J. M. Doggen,
  • Lodewijk J. Wagenaar

摘要

Rotation of the aortic root (AoR) has previously been observed in children with Tetralogy of Fallot (TOF) using 2-dimensional echocardiography. The present study uses cardiovascular magnetic resonance (CMR) imaging to assess whether a clockwise AoR rotation is a common feature in adults with TOF. AoR rotation was measured in the CMR images of consecutive adult patients with corrected TOF and controls. The AoR rotation was assessed in the parasternal short-axis view by measuring the angle of the non-coronary sinus (angle NCS) relative to the interatrial septum (IAS). The angle between IAS and posterior atrial wall was measured to asses IAS reliability as a key anatomical landmark. Inter-observer agreement was determined using intra-class correlation coefficients (ICC). A total of 25 adults with TOF (mean age:33.2 ± 13.1 years;52% male) and 30 controls (mean age:54.5 ± 19.0 years;50% male) were assessed. The angle NCS was greater in TOF patients than in controls (46.2 ± 17.1⁰vs.23.4 ± 15.0⁰, p < 0.001), reflecting a clockwise AoR rotation. As expected, between TOF patients and controls there was no significant difference in the angle IAS (81.1 ± 8.4⁰vs.78.4 ± 9.5⁰, p = 0.46). Inter-observer reliability of CMR measurements was good for the clinically important angle NCS (ICC 0.77, 95%-CI:0.63–0.86) and moderate for the angle IAS (ICC 0.68, 95%-CI:0.51–0.80). This is the first study to demonstrate with CMR that a clockwise rotation of the AoR is a common feature in patients with TOF. This clinical investigation shows the value of CMR for the assessment of the spatial AoR position in adult patients with congenital heart disease.