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Background <p>Compression sleeves are widely used for breast cancer-related lymphedema, but evidence on their effectiveness of prevention and treatment in&#xa0;volume reduction is limited.</p> Objective <p>To compare the effects of compression sleeves and conventional care on breast cancer-related lymphedema, providing evidence-based support for clinical application.</p> Methods <p>A systematic search of 9 databases was conducted up to June 9, 2025. Meta-analysis was performed using RevMan 5.4, and evidence quality was assessed with GRADE profiler 3.6.</p> Results <p> 1532&#xa0;patients were included. Compression sleeves significantly reduced lymphedema incidence post-surgery (<i>P</i> =0 .02) and edema volume/circumference (<i>P</i> &lt;0 .001), and improved shoulder flexion (<i>P</i> =0.02). No significant effects were seen on shoulder abduction (<i>P</i> =0 .18), subjective symptoms (<i>P</i> =0.62), or quality of life (<i>P</i> = 0.32). Evidence quality was moderate for incidence and volume/circumference reduction, and low for other outcomes.</p> Conclusion <p>This meta-analysis shows that compression sleeves reduce lymphedema incidence and volume/circumference, and improve shoulder flexion. They should be considered in lymphedema management, though further research is needed for other outcomes.</p>

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Compression sleeves for prevention and treatment of breast cancer-related lymphedema: a systematic review and meta-analysis

  • 期刊论文

  • 发表日期：

    2025年12月13日

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  • Haifeng Cheng,
  • Jianmei Gong,
  • Lin Yu,
  • Xiaoyu Feng,
  • Wenna Ou,
  • Huan Wang,
  • Hongjing Zhong,
  • En Ming Zhang

摘要

Background

Compression sleeves are widely used for breast cancer-related lymphedema, but evidence on their effectiveness of prevention and treatment in volume reduction is limited.

Objective

To compare the effects of compression sleeves and conventional care on breast cancer-related lymphedema, providing evidence-based support for clinical application.

Methods

A systematic search of 9 databases was conducted up to June 9, 2025. Meta-analysis was performed using RevMan 5.4, and evidence quality was assessed with GRADE profiler 3.6.

Results

1532 patients were included. Compression sleeves significantly reduced lymphedema incidence post-surgery (P =0 .02) and edema volume/circumference (P <0 .001), and improved shoulder flexion (P =0.02). No significant effects were seen on shoulder abduction (P =0 .18), subjective symptoms (P =0.62), or quality of life (P = 0.32). Evidence quality was moderate for incidence and volume/circumference reduction, and low for other outcomes.

Conclusion

This meta-analysis shows that compression sleeves reduce lymphedema incidence and volume/circumference, and improve shoulder flexion. They should be considered in lymphedema management, though further research is needed for other outcomes.