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Purpose <p>The characteristics of patients with bilateral and unilateral breast cancer at the time of diagnosis or during follow-up have been compared, focusing on the differences in disease-free survival and overall survival between these groups.</p> Methods <p>A total of 1,947 patients diagnosed with invasive carcinoma were included in the study. 1876 ​​(96.4%) of our patients had unilateral and 71 (3.6%) had bilateral breast cancer. Among the bilateral breast cancer patients n = 47 were metachronous, while n = 24 were synchronous.</p> Results <p>SBBC, which had the lowest OS duration, showed a statistically significant difference compared to MBCC, similar to that observed in unilateral breast cancer (<i>p</i> = <i>0.027</i>).</p> Conclusion <p>The fact that SBBC has the lowest survival rate despite more aggressive treatments should be considered a poor prognostic factor for survival on its own.</p>

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Comparison of survival between unilateral and bilateral breast cancers using propensity score matching: a retrospective single-center analysis

  • 期刊论文

  • 出版模式：

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  • 发表日期：

    2025年1月9日

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  • Talar Ozler,
  • Rusen Cosar,
  • Necdet Sut,
  • Dilek Nurlu,
  • Şule Parlar,
  • Sinan Ateş,
  • Mert Hacı Dertli,
  • Yusuf Kavuzlu,
  • Sekip Kavukcu,
  • Mert Chousein,
  • Gokay Yıldız,
  • Nermin Tunçbilek,
  • Muhammet Bekir Hacıoglu,
  • Ebru Tastekin,
  • Sernaz Topaloğlu

摘要

Purpose

The characteristics of patients with bilateral and unilateral breast cancer at the time of diagnosis or during follow-up have been compared, focusing on the differences in disease-free survival and overall survival between these groups.

Methods

A total of 1,947 patients diagnosed with invasive carcinoma were included in the study. 1876 ​​(96.4%) of our patients had unilateral and 71 (3.6%) had bilateral breast cancer. Among the bilateral breast cancer patients n = 47 were metachronous, while n = 24 were synchronous.

Results

SBBC, which had the lowest OS duration, showed a statistically significant difference compared to MBCC, similar to that observed in unilateral breast cancer (p = 0.027).

Conclusion

The fact that SBBC has the lowest survival rate despite more aggressive treatments should be considered a poor prognostic factor for survival on its own.