Global Functional Connectivity is Associated with Mind Wandering Domain of Comfort

The resting-state paradigm is frequently applied to study spontaneous activity of the brain in normal and clinical conditions. To assess the relationship between brain activity and subjective experiences, various questionnaires are used. Previous studies using Amsterdam Resting State Questionnaire were focusing on fMRI functional connectivity or EEG microstates and spectral aspect. Here, we utilized Global Field Synchronization as the parameter to estimate global functional connectivity. By re-analyzing the resting-state data from 226 young healthy participants we showed a strong evidence of relationship between ARSQ domain of Comfort and GFS values in the alpha range (r = 0.210, BF₁₀ = 12.338) and substantial evidence for positive relationship between ARSQ domain of Comfort and GFS in the beta frequency range (r = 196, BF₁₀ = 6.307). Our study indicates the relevance of assessments of spontaneous thought occurring during the resting-state for the understanding of the individual intrinsic electrical brain activity.