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<p>Data from simulation cardiomyocyte responses in a&#xa0;state of simulated fibrillation to depolarizing biphasic truncated exponential defibrillation pulses with an energetically optimal pause duration between pulse phases were used to plot graphs of the relationship between the fraction of the fibrillation cycle in which the defibrillation pulse causes a&#xa0;long-term extension of the refractory period of the cardiomyocyte (defibrillation completeness index) and the relative energy of the defibrillation pulse. Simulation was carried out for first-phase pulse durations of 4,&#xa0;6, and 8 msec and second-phase durations of 2,&#xa0;3, 4, 5, and 6 msec. The simulation results showed that the energetically optimal duration of the second phase was 4–5 msec regardless of the duration of the first phase in the range 4–8 msec.</p>

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Evaluation of the influence of the duration of the second phase of a depolarizing biphasic truncated exponential defibrillation pulse with an energetically optimal duration of the pause between phases on its energy efficiency

  • 期刊论文

  • 发表日期：

    2025年9月17日

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  • B. B. Gorbunov,
  • A. Yu. Gerasimenko,
  • S. V. Selishchev

摘要

Data from simulation cardiomyocyte responses in a state of simulated fibrillation to depolarizing biphasic truncated exponential defibrillation pulses with an energetically optimal pause duration between pulse phases were used to plot graphs of the relationship between the fraction of the fibrillation cycle in which the defibrillation pulse causes a long-term extension of the refractory period of the cardiomyocyte (defibrillation completeness index) and the relative energy of the defibrillation pulse. Simulation was carried out for first-phase pulse durations of 4, 6, and 8 msec and second-phase durations of 2, 3, 4, 5, and 6 msec. The simulation results showed that the energetically optimal duration of the second phase was 4–5 msec regardless of the duration of the first phase in the range 4–8 msec.